Papilloma에 관한 증례보고
Papilloma: case report
김종태, 이종갑, 주일로, 김조자,
소속 상세정보
김종태 ( ) - 연세대학교
이종갑 ( ) - 연세대학교
주일로 ( ) - 연세대학교
김조자 ( ) - 연세대학교
KMID : 0358919950220020541
Abstract
The squamous papilloma is a relatively common benign neoplasm that arises from the surface epithelium. It is typically an exophytic lesion whose surface may vary cauliflower-like to fingerlike in appearance, and while generally being a
pedunculated
lesion, it may arise from a sessile base.
The most common sites of occurrence appear to be on the tongue and palatal complex, followed by the buccal mucosa, gingiva, and lips. It is also can be seen with some frequency on the alveolar ridge, floor of the mouth, and retromolar pad
regions.
Histologically, the papilloma is seen as a proliferation of the spinous cell layer in a papillary pattern often accompanies hyperkeratosis, acanthosis, and basilar hyperplasia. Mitotic figures also may be prominent. The supporting fibrous
connective-tissue stroma often contains prominent numbers of small blood vessels as well as an inflammatory cell infiltrate.
The cause of papilloma is not well known, but suggested that chronic inflammatory irriitation, mechanical irritation, and viral infection may be the causes. Recently association with papillomavirus is studied by morphological study,
immuno-histochemistry, and DNA hybridization.
These three cases were recovered by surgial excision without recurrence.
By immunohistochemistry, Case 1 and Case 3 showed positive reaction to HPV antigen.
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